CELECOXIB
Generic Name: celecoxib (oral) (seh leh COCK sib) Brand Names: Celecoxib
Celecoxib comes as a capsule to take by mouth. It is usually taken once or twice a day with or without food. For the treatment of familial adenomatous polposis, celecoxib is taken twice a day with food. To help you remember to take celecoxib, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take celecoxib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Celecoxib is used to relieve the pain, tenderness, inflammation (swelling), and stiffness caused by arthritis and to treat painful menstrual periods and pain from other causes. It is also used to reduce the number of polyps in the colon and rectum in patients with a disease called familial adenomatous polposis. Celecoxib is in a class of nonsteroidal anti-inflammatory medications (NSAIDs) called COX-2 inhibitors. It works by stopping the body's production of a substance that causes pain and inflammation. COX-2 inhibitors may cause less stomach bleeding and ulcers than similar medications.  Notify your doctor immediately if you develop abdominal pain, tenderness, or discomfort; nausea; bloody vomit; bloody, black, or tarry stools; unexplained weight gain; swelling or water retention; fatigue or lethargy; a skin rash; itching; yellowing of the skin or eyes;"flu-like" symptoms; or unusual bruising or bleeding. These symptoms could be early signs of dangerous side effects. |
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Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication. celecoxib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: upset stomach; stomach pain; diarrhea; gas or bloating; sore throat. CelecoxibSome side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately: black and tarry stools; red blood in stools; bloody vomit; vomiting material that looks like coffee grounds; excessive tiredness; unusual bleeding or bruising; itching; lack of energy; loss of appetite; pain in the upper right part of the stomach; yellowing of the skin or eyes; flu-like symptoms; rash; pale skin; unexplained weight gain; swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs; hoarseness; difficulty swallowing or breathing. Celecoxib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. Do not take celecoxib without first talking to your doctor if you have: had an allergic reaction to a sulfa-based medicine such as sulfamethoxazole (Bactrim, Septra, Gantanol, and others), sulfisoxazole (Gantrisin), and others; experienced asthma, hives, or an allergic reaction after taking aspirin or another NSAID such as ibuprofen (Motrin, Advil, Nuprin, and others), naproxen (Aleve, Naprosyn, Anaprox), ketoprofen (Orudis KT, Orudis, Oruvail), diclofenac (Voltaren, Cataflam), diflunisal (Dolobid), etodolac (Lodine, Lodine XL), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), meloxicam (Mobic), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), or tolmetin (Tolectin). You may experience a similar reaction to celecoxib. Before taking celecoxib, tell your doctor if you: smoke; drink alcohol; have an ulcer or bleeding in the stomach; have liver disease; have kidney disease; have asthma; have congestive heart failure; have fluid retention; have heart disease; have high blood pressure; have a coagulation (bleeding) disorder or are taking an anticoagulant (blood thinner) such as warfarin (Coumadin); are taking a steroid medicine such as prednisone (Deltasone and others), methylprednisolone (Medrol and others), prednisolone (Prelone, Pediapred, and others), and others. You may not be able to take celecoxib, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions, or are taking any of the medicines, listed above. Celecoxib is in the FDA pregnancy category C. This means that it is not known whether it will harm an unborn baby. Celecoxib should not be taken late in pregnancy (the third trimester) because it may affect the formation of the baby's heart. Do not take celecoxib without first talking to your doctor if you are pregnant. It is not known whether celecoxib passes into breast milk. Do not take celecoxib without first talking to your doctor if you are breast-feeding. Celecoxib has not been studied in children younger than 18 years of age. If you are over the age of 65 years, you may be more likely to experience side effects from celecoxib. You may require a lower dosage or special monitoring during your therapy. Keep Celecoxib in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication. Before taking celecoxib, tell your doctor if you are taking any of the following drugs: aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), choline salicylate-magnesium salicylate (Trilisate, Tricosal, others), and magnesium salicylate (Doan's, Bayer Select Backache Formula, others); an over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, naproxen, or ketoprofen; a diuretic (water pill) such as furosemide (Lasix), hydrochlorothiazide (HydroDiuril, others), chlorothiazide (Diuril, others), chlorthalidone (Hygroton, Thalitone), and others; an angiotensin-converting-enzyme inhibitor (ACE inhibitor) such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), quinapril (Accupril), and others. A steroid medicine such as prednisone (Deltasone and others), methylprednisolone (Medrol and others), prednisolone (Prelone, Pediapred, and others), and others; an anticoagulant (blood thinner) such as warfarin (Coumadin); lithium (Eskalith, Lithobid, others); fluconazole (Diflucan). You may not be able to take an celecoxib, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above. Drugs other than those listed here may also interact with celecoxib. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.
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