HYDROCHLOROTHIAZIDE
Generic Name: hydrochlorothiazide (hye dro klor oh THYE a zide) Brand Names: Carozide, Diaqua, Esidrix, Ezide, Hydro Par, HydroDIURIL, Loqua, Microzide, Oretic Hydrochlorothiazide (Apo-Hydro®, Aquazide H®, Microzide®, Oretic®), sometimes abbreviated HCT, HCTZ, or HZT is a popular diuretic drug that acts by inhibiting the kidney's ability to retain water. This reduces the volume of the blood, decreasing peripheral vascular resistance.
Take hydrochlorothiazide capsules or tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. Take your doses at regular intervals. Do not take your medicine more often than directed. Remember that you will need to pass urine frequently after taking hydrochlorothiazide. Do not take your doses at a time of day that will cause you problems. Do not take at bedtime. HYDROCHLOROTHIAZIDE is a diuretic. Diuretics increase the amount of urine passed, which causes the body to lose water and salt. Hydrochlorothiazide helps to treat high blood pressure (hypertension). It is not a cure. It also reduces the swelling and water retention caused by various medical conditions, such as heart, liver, or kidney disease. Generic hydrochlorothiazide capsules or tablets are available.  To reduce nighttime urination, take hydrochlorothiazide early in the day unless otherwise directed by your doctor. Use caution when driving, operating machinery, or performing other hazardous activities. Hydrochlorothiazide may cause dizziness. If you experience dizziness, avoid these activities. Do not take hydrochlorothiazide without first talking to your doctor if you have an allergy to sulfa-based drugs such as sulfa antibiotics. You may have an allergic reaction to hydrochlorothiazide. |
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Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication. If you experience any of the following serious side effects, stop taking hydrochlorothiazide and seek emergency medical attention or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); unusual fatigue; abnormal bleeding or bruising; yellow skin or eyes; confusion; irregular heartbeats or a fluttering feeling in the chest; little or no urine. Other, less serious side effects are more likely to occur. Continue to take hydrochlorothiazide and talk to your doctor if you experience: dizziness, especially when rising from sitting or lying down; tingling or numbness in the arms, legs, hands, or feet; excessive urination; muscle weakness or cramps; increased hunger or thirst; nausea or decreased appetite; abdominal pain; sensitivity to sunlight; impotence. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. Visit your prescriber or health care professional for regular checks on your progress. Check your blood pressure regularly. Ask your prescriber or health care professional what your blood pressure should be, and when you should contact him or her. You must not get dehydrated, ask your prescriber or health care professional how much fluid you need to drink a day. Do not stop taking hydrochlorothiazide except on your prescriber's advice. Watch your diet while you are taking hydrochlorothiazide. Ask your prescriber or health care professional about both potassium and sodium intake. Hydrochlorothiazide can make your body lose potassium and you may need an extra supply. Too high or too low potassium can cause problems. Some foods have a high potassium content such as bananas, coconuts, dates, figs, prunes, apricots, peaches, grapefruit juice, tomato juice, and orange juice. You may get dizzy or lightheaded. Do not drive, use machinery, or do anything that needs mental alertness until you know how hydrochlorothiazide affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can make you lightheaded, dizzy and increase confusion. Avoid or limit intake of alcoholic drinks. Hydrochlorothiazide can make your skin more sensitive to sun or ultraviolet light. Keep out of the sun, or wear protective clothing outdoors and use a sunscreen (at least SPF 15). Do not use sun lamps or sun tanning beds or booths. If you are going to have surgery, tell your prescriber or health care professional that you are taking hydrochlorothiazide. Hydrochlorothiazide can increase the amount of sugar in blood or urine. If you are a diabetic keep a close check on blood and urine sugar. Keep Hydrochlorothiazide in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication. Before taking hydrochlorothiazide tell your doctor if you are taking any of the following medications: lithium (Lithobid, Eskalith, others); digoxin (Lanoxin, Lanoxicaps); the cholesterol-lowering drugs cholestyramine (Questran) or colestipol (Colestid); a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin), naproxen (Naprosyn, Anaprox, Aleve), ketoprofen (Orudis, Orudis KT, Oruvail), indomethacin (Indocin), diclofenac (Cataflam, Voltaren), etodolac (Lodine), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), tolmetin (Tolectin), fenoprofen (Nalfon), ketorolac (Toradol), or flurbiprofen (Ansaid); a diabetes medication such as glipizide (Glucotrol), glyburide (Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase), tolbutamide (Orinase), and others; a steroid medicine such as cortisone (Cortone), dexamethasone (Decadron, Hexadrol), hydrocortisone (Cortef, Hydrocortone), prednisone (Orasone, Deltasone), prednisolone (Delta Cortef, Prelone), methylprednisolone (Medrol), and others. You may not be able to take hydrochlorothiazide, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medications listed above. Also, before taking hydrochlorothiazide, tell your doctor if you are taking any other medicine to treat high blood pressure, water retention, heart problems, prostate problems, or another condition. Some medicines used to treat these conditions may interact with hydrochlorothiazide and the effects on your heart may be increased. Hydrochlorothiazide may increase the effects of other drugs that cause drowsiness, including sedatives (used to treat insomnia), pain relievers, seizure medicines, antidepressants, alcohol, antihistamines, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor. Drugs other than those listed here may also interact with hydrochlorothiazide or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.
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