IMITREX
Generic Name: sumatriptan (SLO ma trip tin) Brand Names: Imitrex, Imitrex Nasal, Imitrex Statdose Sumatriptan (Imitrex®, Imigran®) is a triptan drug originally developed by Glaxo for the treatment of migraine headaches. Several dosage forms for sumatriptan have been approved, including tablets, solution for injection, and nasal inhalers. Sumatriptan was the first triptan available (in 1991), and, in the United States and most developed countries, is available only by medical prescription.
Do not take this medication without first talking to your doctor if you have heart disease including angina (chest pain), history of a heart attack, or high blood pressure. Serious, even fatal, side effects involving the heart have been reported with sumatriptan and other similar medicines. Do not take sumatriptan without first talking to your doctor if you: are taking or have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days; have taken an ergot-based medication within the last 24 hours--ergot-based medicines include methysergide (Sansert), ergotamine (Ergostat, Medihaler Ergotamine), dihydroergotamine mesylate (D.H.E., Migranal Nasal Spray), and ergotamine combination products (Cafergot, Ercaf, Wigraine, Cafatine, Cafatine-PB, Cafetrate); have taken almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), or zolmitriptan (Zomig) within the last 24 hours; have basilar or hemiplegic migraine headaches; have a history of stroke or transient ischemic attack (TIA or "mini-stroke"); are experiencing a headache that is not like other migraines you have had; have an allergy to sumatriptan or other similar medicines such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig). Taking sumatriptan may be dangerous if you have any of the conditions, or have taken any of the medications listed above. Before taking sumatriptan, tell your doctor if you have: risk factors for heart disease such as high blood pressure, a family history of heart disease, high cholesterol (a type of fat in the blood), are overweight, have diabetes, smoke cigarettes, are postmenopausal, or are a male over 40 years of age; have circulation problems such as Raynaud's syndrome; liver disease; kidney disease; seizures or epilepsy. You may not be able to take sumatriptan, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.umatriptan is in the FDA pregnancy category C. This means that it is not known whether sumatriptan will be harmful to an unborn baby. Do not use this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. Sumatriptan passes into breast milk and may affect a nursing infant. Do not use sumatriptan without first talking to your doctor if you are breast-feeding a baby. Sumatriptan is a headache medicine. It is believed to work by causing vasoconstriction (narrowing) of blood vessels (arteries and veins) around the brain. Sumatriptan also reduces the release of substances in the body that contribute to headache pain, nausea, sensitivity to light and sound, and other migraine symptoms. Sumatriptan is used to treat vascular headaches such as migraine and cluster headaches. Sumatriptan will not prevent migraines or cluster headaches or reduce the number of attacks. It will only treat a migraine or cluster headache that is already occurring. Sumatriptan may also be used for purposes other than those listed in this medication guide.  Sumatriptan is used to treat severe migraine headaches. Many people find that their headaches go away completely after they take sumatriptan. Other people find that their headaches are much less painful, and that they are able to go back to their normal activities even though their headaches are not completely gone. Sumatriptan often relieves other symptoms that occur together with a migraine headache, such as nausea, vomiting, sensitivity to light, and sensitivity to sound. Sumatriptan is not an ordinary pain reliever. |
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Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication. Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Imitrex. More common side effects may include: Burning sensation, dizziness or vertigo, feeling of heaviness, feeling of tightness, flushing, mouth and tongue discomfort, muscle weakness, nausea (nasal spray), neck pain and stiffness, numbness, pressure sensation, redness at the site of injection, sinus or nasal discomfort (nasal spray), sore throat, tingling, unusual taste (nasal spray), vomiting (nasal spray), warm/cold sensation. Less common or rare side effects may include: Abdominal discomfort, agitation, allergic reactions (severe), anxiety, asthma, backache, backflow of stomach contents, bleeding between periods, bleeding in ears, nose or throat, breast tenderness, burning/numbness of tongue, changes in heart rhythm, chills, cold sensation, confusion, constipation, cough, depression, diarrhea, difficult or labored breathing, difficult or painful urination, difficulty concentrating, difficulty speaking, difficulty swallowing, drowsiness/calmness, dry mouth, ear infection, ear pain, exaggerated feeling of well-being, eye irritation, facial pain, fainting, fatigue, feeling strange, fever, general feeling of illness, headache, hearing loss, hearing disturbance, heavy feeling, hives, incoordination, increased urination, intolerance of noise or light, itching, jaw discomfort, joint problems, muscle cramps, muscle pain or tenderness, painful menstruation, pressure in chest, rapid and throbbing heartbeat, rash, ringing in the ears, rise or fall in blood pressure (temporary), sensation of lightness, sensitivity to noise or heat, shivering, shortness of breath, sinus inflammation, sinus or nasal discomfort, skin eruptions, skin redness or tenderness, sleep disturbances, smell disturbances, stomach problems, sweating, swelling, tearing, thirst, tight feeling in head, tightness in chest, tremors, vision changes or loss. In addition to the above side effects, people taking Imitrex for cluster headache may experience nausea, a "pins and needles" sensation, vomiting, or wheezing. Sumatriptan may cause dizziness or drowsiness. Use caution when driving, operating machinery, or performing other hazardous activities until you can evaluate the effects of the medication. Keep Imitrex in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication. Do not use sumatriptan if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) within the last 14 days. The combination could cause seizures, nausea, vomiting, sweating, flushing, and dizziness. Do not use sumatriptan without first talking to your doctor if you have taken any of the following medicines within the previous 24 hours: an ergot-based medication such as methysergide (Sansert), ergotamine (Ergostat), dihydroergotamine (D.H.E., Migranal Nasal Spray), and ergotamine combination products (Cafergot, Ercaf, Wigraine, Cafatine, Cafatine-PB, Cafetrate); another migraine medicine such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), or zolmitriptan (Zomig, Zomig-ZMT). Using sumatriptan within 24 hours of any of the medicines listed above may be dangerous. Before using sumatriptan, tell your doctor if you are taking a selective serotonin reuptake inhibitor (SSRI) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil, Pexeva), or sertraline (Zoloft). You may not be able to use sumatriptan, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed. Drugs other than those listed here may also interact with sumatriptan. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.
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