ORLISTAT
Generic Name: orlistat (OR lih stat) Brand Names: Xenical Orlistat (marketed as Xenical by Roche) is a drug designed to treat obesity. Its primary function is to prevent the absorption of dietary fats, thereby reducing caloric intake. It is intended for use in conjunction with a physician-supervised reduced calorie diet.
Orlistat is taken by mouth and swallowed with a drink of liquid. Follow the directions on the prescription label. You can take orlistat with each main meal that contains about 30% of the calories from fat. Or you can take the capsule one hour after the meal. Do not take your medicine more often than directed. If you occasionally miss a meal or have a meal without fat, you can omit that dose of orlistat. Doses greater than 120 mg three times per day have not been shown to increase weight loss. You should use orlistat with a reduced-calorie diet that contains no more than about 30% of the calories from fat. Divide your daily intake of fat, carbohydrates, and protein evenly over your 3 main meals. You should try to follow a healthy eating plan as prescribed by your doctor such as the one developed by the American Heart Association. Following this eating plan can help reduce the possible GI side effects from orlistat. Orlistat (Xenical®) is a prescription drug used to help obese people lose weight and keep the weight off while eating a reduced-calorie diet. Orlistat decreases the amount of fat that is absorbed from your diet.  Orlistat may decrease your body's absorption of some fat-soluble vitamins. To ensure adequate nutrition, your doctor may recommend taking a multivitamin that contains vitamins D, E, K, and beta-carotene. Take your vitamin supplement once a day, at least 2 hours before or after a dose of orlistat. Do not take more of this medication than has been prescribed for you. Doses greater than 120 mg three times a day have not been shown to provide any additional weight-loss benefit. |
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Take the missed dose up to one hour after a meal. If more than one hour has passed since your last meal, skip the dose you missed and take only your next regularly scheduled dose as directed. Do not take a double dose of this medication. If you miss a meal, or if you have a meal without fat, you can skip your dose of orlistat for that meal also. Stop taking orlistat and seek emergency medical attention if you experience a rare allergic reaction including shortness of breath; closing of your throat; swelling of your lips, tongue, or face; or hives. Other, less serious side effects are more likely to occur. Continue to take orlistat and talk to your doctor if you : oily spotting; oily or fatty stools; orange or brown colored oil in your stool; gas with discharge, an oily discharge; an urgent need to go to the bathroom; an inability to control bowel movements, or; an increased number of bowel movements. The bowel changes listed above are a natural effect of blocking fat and indicate that orlistat is working. They generally occur early in treatment, particularly after meals containing higher amounts of fat than are recommended. These symptoms are usually temporary and lessen or disappear as you continue treatment and keep to your recommended diet of meals containing 30% fat. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. Do not take orlistat without first talking to your doctor if you : chronic malabsorption syndrome (an inability to absorb food and nutrients properly), gallbladder problems. You may not be able to take orlistat if you have any of the conditions listed above. Before taking orlistat, talk to your doctor if you: have a history of kidney stones; have diabetes; have anorexia or bulimia; take any other weight-loss medicine; take cyclosporine (Sandimmune, Neoral). You may not be able to take orlistat, or you may require a dosage adjustment or special monitoring during your treatment if you have any of the conditions listed above. Orlistat is in the FDA pregnancy category B. This means that it is not expected to harm an unborn baby. Do not take orlistat without first talking to your doctor if you are pregnant. It is not known whether orlistat passes into breast milk. Do not take orlistat without first talking to your doctor if you are breast-feeding a baby. Keep Orlistat in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication. Do not take orlistat without first talking to your doctor if you are taking any of the following medicines: cyclosporine (Neoral, Sandimmune), warfarin (Coumadin). You may not be able to take orlistat, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above. Orlistat may decrease your body's absorption of some fat-soluble vitamins. To ensure adequate nutrition, your doctor may recommend taking a multivitamin that contains vitamins D, E, K, and beta-carotene. Take your vitamin supplement once a day, at least 2 hours before or after a dose of orlistat. Drugs other than those listed here may also interact with orlistat. Talk to your doctor and pharmacist before taking or using any other prescription or over-the-counter medicines including vitamins, minerals, and herbal products.
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