PROGESTERONE
Progesterone is a C-21 steroid hormone involved in the female menstrual cycle, pregnancy (supports gestation) and embryogenesis of humans and other species. Progesterone belongs to a class of hormones called progestagens, and is the major naturally occurring human progestagen.
Progesterone should not be confused with progestins, which are synthetically produced progestagens.
Progesterone has been associated with increased blood clotting. Increased blood clotting can cause stroke, heart attack, blood clots in the lungs, vision loss or blindness and many other problems. Any of these conditions may cause death or serious long-term disability. Stop taking progesterone and seek emergency medical attention or contact your doctor immediately if you experience any of the following serious side effects: - shortness of breath or pain in the chest; a sudden severe headache; visual changes; a painful, red, swollen leg; numbness or tingling in an arm or leg. Progesterone is a female hormone important for the regulation of ovulation and menstruation. Progesterone is used to prevent overgrowth of the endometrium of postmenopausal women who have not had a hysterectomy and are receiving estrogen replacement therapy. Progesterone is also used to treat the absence of menstruation due to progesterone deficiency. Progesterone may also be used for purposes other than those listed in this medication guide.  o not take the Prometrium brand of progesterone if you are allergic or sensitive to peanuts. Prometrium capsules contain peanut oil and should never be used by individuals with a peanut allergy. |
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Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication. Stop taking progesterone and seek emergency medical attention or contact your doctor immediately if you experience any of the following serious side effects: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); shortness of breath or pain in the chest; a sudden severe headache; visual changes; a painful, red, swollen leg; numbness or tingling in an arm or leg; prolonged, heavy, vaginal bleeding; stomach or side pain; yellowing of the skin or eyes. Other, less serious side effects may be more likely to occur. Continue to take progesterone and talk to your doctor if you experience: dizziness; drowsiness; headache; breast pain or tenderness; abdominal pain or distention; diarrhea; vaginal discharge; mood changes, anxiety, irritability, or depression. TProgesterone is poorly absorbed by oral ingestion unless micronised and in oil, or with fatty foods; it does not dissolve in water. Products such as Prometrium, Utrogestan and Microgest are therefore capsules containing micronised progesterone in oil - in all three mentioned that is peanut oil, which may cause serious allergic reactions in some people, but compounding pharmacies, which have the facilities and licenses to make their own products, can use alternatives. Vaginal and rectal application is also effective, with products such as Cyclogest, which is progesterone in cocoa butter in the form of pessaries. Progesterone can be given by injection, but because it has a short half-life they need to be daily. Implants, for a longer period are also available. Marketing of progesterone phamaceutical products, country to country, varies considerably, with many countries having no oral progesterone products marketed, but they can usually be specially imported by pharmacies through international wholesalers Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
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